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CHI Yonggui, Robin
Chi photo.jpg

Associate Professor
National Research Foundation (NRF) Fellow

Education: B.Sc., Hong Kong Baptist University & Tsinghua University; Ph.D., University of Wisconsin-Madison; Post-doc. (Univ. of California-Berkeley)

Research Area: Catalysis & Organic Synthesis, Peptides, Proteins, Polymers, Nanoscale Structures & Functional Materials

Phone: (65) 6592 7769

E-mail: robinchi@ntu.edu.sg

Webpage: http://www.ntu.edu.sg/home/robinchi

   


Research Interest

The Chi group focuses on the development of conceptually new, fundamentally important, and practically useful chemistry and chemical strategies that addresses challenges in the fields of organic synthesis, sophisticated molecule modifications, and functional materials. Concepts and fundamentals are crucial because they lead to new frontiers and drives science forward. The group is also committed to develop chemical methods and approaches that can be easily used in both academia and industry to ultimately generate economic benefits to the society.

In one program the group focuses on asymmetric catalysis and organic synthesis. Research directions in this program include: development of more efficient and selective catalysts to achieve effective and sustainable synthesis of molecules of biomedical importance; creation of new catalytic activation modes through the design of new organic catalysts and metal/organic dual catalytic systems; design of multi-functional catalysts and catalytic transformations that allows for selective modification of sophisticated molecules under mild conditions; and structure- and function-oriented synthesis.

Other major research programs in the group involve peptides, polymers and biopolymers, nanoscale structures and materials. Additional information about the group’s research can be found on http://chigroupweb.org/ or requested via email.

Prof. Chi is also committed to undergraduate and graduate educations.


Selected Publications

  1. Scroggins, T. S.; Chi, Y. Fréchet, J. M. J.” Polarity-Directed One-Pot Asymmetric Cascade Reactions Mediated by Two Catalysts in an Aqueous Bufferz”, Angew. Chem. Int. Ed., 2009, in press (VIP Paper)

  2. Chi, Y.; Scroggins, T. S.; Boz, E.; Fréchet, J. M. J. “Control of Aldol Reaction Pathways of Enolizable Aldehdyes with an Enzyme-Like Polymer Catalyst in Aqueous Environment”, J. Am. Chem. Soc, 2008, 130, 17287-17289.

  3. Chi, Y.; Scroggins, T. S.; Fréchet, J. M. J. “One-Pot Multi-Component Asymmetric Cascade Reactions Catalyzed by Soluble Star Polymers with Non-Interpenetrating Catalytic Cores”, J. Am. Chem. Soc., 2008, 130, 6322-6323.(Lawrence Berkeley National Laboratory 2008 Research Highlights)

  4.  Chi, Y.; Guo, L.; Kopf, N. A.; Gellman, S. H. “Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene: Efficient Access to γ2-Amino Acids”, J. Am. Chem. Soc., 2008, 130, 5608-5609. (Highlighted: C&E News, 2008, 86, 50-51; Synfacts 2008, 6, 0648.)